Search results for " gynecology"
showing 10 items of 1547 documents
Fisioterapia en incontinencia urinaria de embarazo y posparto: una revisión sistemática
2016
Resumen Objetivo El objetivo del presente trabajo es la realizacion de una revision sistematica mediante el acceso a las bases de datos mas populares sobre ciencias de la salud, en busca de la evidencia cientifica actual sobre la fisioterapia como tratamiento para la incontinencia urinaria de embarazo y posparto. Material y metodos Busqueda en Pubmed, Google Academico, SciELO y Biblioteca Cochrane sobre articulos que aporten una idea general de esta dolencia y de su tratamiento fisioterapico. Para ello se seleccionaron una serie de palabras clave: «incontinencia urinaria de embarazo», «incontinencia urinaria de posparto» o «fisioterapia en incontinencia urinaria de embarazo». Fueron selecci…
Qualité de vie après chirurgie de l’endométriose pelvienne profonde : évaluation d’une version française de l’EHP-30
2016
Resume Objectif Evaluer l’evolution de la qualite de vie des patientes apres chirurgie de l’endometriose pelvienne profonde, a l’aide du questionnaire EHP-30 dans sa version francaise, ainsi que la capacite de l’EHP-30 a realiser cette mesure. Materiel et methode Etude prospective monocentrique, menee dans le service de gynecologie obstetrique du CHU de Dijon pendant la periode d’octobre 2012 a octobre 2013. Un questionnaire EHP-30 etait donne aux patientes avant l’intervention. Ce meme questionnaire etait envoye a leur domicile, a distance de la chirurgie (3 a 6 mois apres) afin qu’elles informent sur leur qualite de vie postoperatoire. La difference des scores preoperatoires et postoperat…
Diagnóstico de lesiones anexiales por residentes de ginecología mediante valoración subjetiva, LR2 y Simple rules
2020
Resumen Objetivo Evaluar y comparar la precision diagnostica de las Simple rules, el sistema de regresion logistica LR2 de IOTA y la valoracion subjetiva aplicados por residentes de ginecologia en la clasificacion de benignidad o malignidad de lesiones anexiales. Material y metodos Fueron evaluadas las imagenes ecograficas de 94 lesiones anexiales por 3 residentes de ginecologia con un ano de experiencia y con un entrenamiento teorico y practico previo similar. La benignidad o malignidad fue determinada mediante 3 metodos: valoracion subjetiva, Simple rules y modelo LR2. El grado de precision en la clasificacion de las lesiones se valoro mediante la sensibilidad, la especificidad, el valor …
Implantation failure of endometrial origin: what is new?
2018
To review recent findings related to possible causes of recurrent implantation failure of endometrial origin in normal uterus.Recent evidences suggest that in apparently normal endometria, RIF may associate with molecular and functional changes in the uterus such as abnormal endometrial microbiota, including the presence of chronic endometritis, poor synchronization between the blastocyst and endometrium, and/or excessive uterine peristalsis. An altered endometrial microbiota detected by molecular techniques has been recently related to poorer embryo implantation, even in apparently normal endometria. The use of the endometrial receptivity analysis test to obtain an objective signature of e…
Type of chromosome abnormality affects embryo morphology dynamics.
2016
Objective To study the differences in the cleavage time between types of embryo chromosomal abnormalities and elaborate algorithm to exclude aneuploid embryos according to the likelihood to be euploid. Design Retrospective cohort study. Setting University affiliated private center. Patient(s) Preimplantational genetic screening patients (n = 112) including cases of advanced maternal age, repeated implantation failure, and recurrent miscarriage. A total of 485 embryos were analyzed. Intervention(s) None. Main Outcome Measure(s) All biopsied embryos were cultured in an incubator with time-lapse technology, cleavage timing from insemination to day 3 and all kinetic parameters that have been de…
Effect of oocyte morphology on post-warming survival and embryo development in vitrified autologous oocytes.
2019
Abstract Research question Does the presence of dysmorphisms affect post-warming survival and embryo development in vitrified autologous oocytes? Design A retrospective study comparing post-warming survival, fertilization and embryo development between morphologically normal (n = 269) and dysmorphic oocytes (n = 147). Results The survival rate was 81.4% in the morphologically normal oocytes and 87.1% in the dysmorphic oocyte group (OR 1.53; 95% CI 0.86 to 2.72). The fertilization rate was 69.9 versus 66.4% (OR 0.85; 95% CI 0.53 to 1.36), the proportion of good-quality embryos on day 3 was 30.3% versus 32.0% (OR 1.08; 95% CI 0.59 to 1.97) and the blastocyst formation rate was 54.5% versus 60…
Transcriptomic behavior of genes associated with chromosome 21 aneuploidies in early embryo development.
2019
To analyze how chromosome 21 (HSA21) ploidy affects global gene expression of early human blastocysts.Prospective study.University-affiliated in vitro fertilization clinic.A total of 26 high-quality donated embryos from in vitro fertilization (IVF) patients: trisomy 21 (n = 8), monosomy 21 (n = 10), and euploid (n = 8) blastocysts.None.Blastocyst transcriptome changes and its associated functions.Trisomy 21, monosomy 21, and euploid blastocysts were classified by comparative genomic hybridization. The global transcriptome of whole blastocysts was analyzed with small cell number RNA sequencing, and they were compared to understand the gene expression behavior at early development and its imp…
Dysregulated genes and their functional pathways in luteinized granulosa cells from PCOS patients after cabergoline treatment
2018
Polycystic ovarian syndrome (PCOS) is a common reproductive disorder frequently associated with a substantial risk factor for ovarian hyperstimulation syndrome (OHSS). Dopamine receptor 2 (D2) agonists, like cabergoline (Cb2), have been used to reduce the OHSS risk. However, lutein granulosa cells (LGCs) from PCOS patients treated with Cb2 still show a deregulated dopaminergic tone (decreased D2 expression and low dopamine production) and increased vascularization compared to non-PCOS LGCs. Therefore, to understand the PCOS ovarian physiology, it is important to explore the mechanisms that underlie syndrome based on the therapeutic effects of Cb2. Here, LGCs from non-PCOS and PCOS patients …
Arrangement of myofibroblastic and smooth muscle-like cells in superficial peritoneal endometriosis and a possible role of transforming growth factor…
2018
Purpose: Superficial peritoneal endometriotic (pEM) lesions are composed of endometrial glands and stroma, in addition to a third component—myofibroblasts and smooth muscles (SM)-like cells. The latter develops secondary to a metaplasia. In this study, we characterised the third component cells in pEM according to differentiation markers in different micro-compartments. Furthermore, a possible effect of TGFβ1 on myofibroblastic metaplasia in endometriotic epithelial cells was studied. Methods: Seventy-six premenopausal patients were included. Peritoneal biopsies were excised from EM patients (n = 23), unaffected peritoneum (peritoneum from EM patients but without EM components, n = 5/23) an…
Characterization of endometriosis-associated immune cell infiltrates (EMaICI)
2016
Objective: To identify and characterize endometriosis-associated immune cell infiltrates (EMaICI). Furthermore, to define occurrence and size of EMaICI in various types of endometriosis. Methods: Immune cells were characterized in samples of 60 premenopausal women with histological proven endometriosis. Therefore, immunohistochemical staining with monoclonal antibodies for CD3, CD4, CD8, CD45RO, CD25, CD56, CD68, and CD20 on sections of paraffin-embedded endometriotic tissue was performed. Results: EMaICI were observed in all the types of endometriosis, and characterized as T lymphocytes (CD3+), helper T lymphocytes (CD4+), cytotoxic T lymphocytes (CD8+), antigen-experienced T lymphocytes”m…